What types of medications cannot be returned for reuse?

The correct choice pertains to medications requiring refrigeration or controlled substances because both categories are subject to strict regulations regarding their handling and distribution. Medications that require refrigeration are particularly sensitive; any deviation from their storage conditions can compromise their effectiveness and safety, making it unsuitable for reuse.

Controlled substances, which are tightly regulated due to their potential for abuse, cannot be returned to inventory once dispensed. This is primarily because returning these medications could lead to potential misuse or diversion. The legal frameworks governing these substances emphasize public safety and the integrity of the pharmaceutical supply chain, thus prohibiting their return for reuse.

Other types of medications, while some may have restrictions on returns or may not be recommended for reuse, do not carry the same level of regulatory concern as those that require refrigeration or are classified as controlled substances.